Huntington’s disease (HD) is caused by an expansion of a short DNA sequence — the letters C-A-G — located in the very first ...

In people with premanifest HD, lower scores on the visual thinking tests were linked with more movement changes over time.

August has been a packed month for Huntington’s disease (HD) research. We’ve looked at what can be learned from disappointing ...

A new study from researchers at the University of Washington and University College London explores different ways to lower the huntingtin proteinhuntingtin protein The protein produced by the HD gene ...

A new Phase 1 study is testing SRP-1005, a huntingtin-lowering therapy given by injection under the skin. It’s early days, but this approach could add an important new arrow to the HD drug development ...

First to speak was Aikaterini Papadopoulou, who talked about her work targeting a fragment of the expanded HTTHTT one abbreviation for the gene that causes Huntington’s disease. The same gene is also ...

This week, HDBuzz is attending the HD2026 Milton Wexler Biennial Symposium in Boston, Massachusetts. Held every other year and organized by the Huntington’s Disease Foundation (HDF), this conference ...

Four weeks ago, Roche announced through a community statement that they were ending both their tominersen programme and development of RG6496 that selectively targets expanded huntingtin.

Today, Roche announced in a community letter difficult news for the Huntington’s disease (HD) community, discontinuing two separate clinical programmes after new data emerged from ongoing studies. The ...

In plain language. Written by scientists. #Buzzilia, day 4: Jeff and Ed's roundup of happenings from the closing day of the HD World Congress in Rio de Janeiro #Buzzilia, day 3: Jeff and Ed's roundup ...

⏱️6 min read | PROTACs act like a precision pruning tool, trimming away toxic huntingtin protein while leaving the healthy form intact. In cells and HD mice, this targeted clean-up improved health and ...

A paper recently published in Nature Medicine caught our attention. In it, researchers celebrated Australia’s new federal law banning life insurance companies from using genetic test results when ...