clinicaltrialsarena

AbbVie eyes extended Qulipta use case on Phase III menstrual migraine win

AbbVie will submit these data to global health authorities. Credit: PeopleImages / Shutterstock.com. AbbVie’s preventative migraine therapy, Qulipta (atogepant), has netted a successful late-stage ...
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Biohaven’s epilepsy drug hit with FDA clinical hold

Opakalim is currently in development for the treatment of focal onset seizures. Credit: Berit Kessler / Shutterstock.com. The US Food and Drug Administration (FDA) has placed a partial clinical hold ...
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Beeline Medicines’ Phase II SLE trial of afimetoran meets primary endpoint

The trial enrolled 248 adults aged 18 to 70 with moderate-to-severe SLE. Credit: Jarun Ontakrai / Shutterstock.com. Beeline Medicines has announced that its global Phase II clinical trial involving ...
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ERS 2026: tozorakimab’s groundbreaking exacerbation reduction sets a new bar in COPD

OBERON and TITANIA were double-blind, placebo-controlled Phase III trials enrolling just over 2,300 patients with a history of two or more moderate or one or more severe COPD exacerbations in the ...
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Orphalan launches Phase III TRADITiONAL trial for Wilson disease

Wilson disease is caused by ATP7B gene mutations. Credit: Saiful52 / Shutterstock.com. Orphalan has launched the TRADITiONAL Study, a global Phase III clinical trial of an investigational once-daily ...
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BMS reports positive data from Phase II QUINTESSENTIAL study for r/r MM

The study is evaluating the efficacy and safety of arlo-cel in patients who have previously received CAR T-cell therapies. Credit: PanuShot / Shutterstock.com. Bristol Myers Squibb (BMS) has reported ...
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Novartis’ $12bn Avidity bet falters on late-stage del-desiran flop

Novartis will now assess the next steps for del-desiran’s development programme. Credit: 24K-Production / Shutterstock.com. Novartis’ Avidity Biosciences-acquired therapy, delpacibart etedesiran ...
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Novo’s Wegovy touts obesity-treating potential in patients as young as six

There are currently limited pharmaceutical treatment options for patients with obesity under 12 years of age. Credit: New Africa / Shutterstock.com. Novo Nordisk’s blockbuster weight loss drug, Wegovy ...
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Rezubio doses first cohort in Phase I trial of inhaled RZ-520

RZ-520 is designed to maintain drug exposure within the lung. Credit: sasirin pamai / Shutterstock.com. Rezubio has dosed the first cohort of patients in a Phase I trial of RZ-520, an inhaled ...
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Novo Nordisk’s ziltivekimab stumbles again on pair of Phase III terminations

The HERMES and ATHENA trials will stop due to a data monitoring committee’s recommendation. Credit: Below the Sky / Shutterstock.com. Novo Nordisk has opted to prematurely end two Phase III trials of ...
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Acepodia secures FDA clearance to begin Phase I ACE723 trial

The trial will involve patients with unresectable or metastatic hepatocellular carcinoma. Credit: MY STOCKERS / Shutterstock.com. Acepodia has secured the US Food and Drug Administration (FDA) ...