Inflammatory arthritis encompasses a group of autoimmune diseases, including rheumatoid arthritis (RA), psoriatic arthritis ...

Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...

GAS2 is a cytoskeletal regulator that interacts with both F-actin and microtubules. Here, cryo-EM structures of GAS2 domains ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Subcutaneous LCMV infection induces T H 1 cell ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Huntington’s disease (HD) is a debilitating ...

This cover highlights the article PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division by M. Gobran, P. Lenart and colleagues. HeLa Kyoto ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Genomics has transformed the diagnostic ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Saccharin has been part of the human diet for ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Rho GTPases form plasma membrane-associated ...

How cardiac cell fates are specified during heart development remains elusive. This study identifies a level-dependent role ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Metastasis is the primary cause of death in ...