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  1. CREST Syndrome: What It Is, Symptoms & Treatment - Cleveland Clinic

    CREST syndrome (limited scleroderma) doesn’t affect as many organs or cause as many complications as diffuse systemic sclerosis can. It progresses slowly, and the symptoms are often manageable with …

  2. CREST syndrome - Wikipedia

    CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder. The acronym "CREST" refers to the five main features: …

  3. CREST Syndrome: Symptoms, Treatment, and More - Verywell Health

    Oct 22, 2025 · This rare connective tissue disease becomes more serious as it progresses to systemic disease. This article explains how CREST syndrome affects the body, and the symptoms, causes, …

  4. CREST Syndrome - Stanford Health Care

    CREST syndrome coupled with pulmonary hypertension (elevated blood pressures within the lungs) can lead to heart and respiratory failure. See your doctor for advanced, integrated diagnosis and treatment.

  5. CREST Syndrome and Scleroderma - WebMD

    Aug 30, 2024 · Some people have a type of scleroderma called CREST syndrome (or limited scleroderma). The good news is that your doctor can help you manage your symptoms, prevent …

  6. What Is CREST Syndrome? A Comprehensive Overview - Health

    Mar 1, 2025 · With CREST syndrome, the immune system injures cells that line your blood vessels, causing your fibroblasts (connective tissue cells) to produce too much collagen (a structural protein). …

  7. What You Need to Know About Crest Syndrome: Symptoms, Causes, …

    CREST syndrome is a type of autoimmune condition that leads to stiff, hardened skin and connective tissues. Specifically, CREST syndrome is a subtype of the autoimmune disease scleroderma.

  8. What is crest syndrome? Symptoms and treatment - Medical News Today

    Dec 23, 2022 · Due to advancements in treatment, the outlook for those with the condition is improving. This article explores how CREST syndrome affects the body, and its causes, diagnosis, and treatments.

  9. CREST Syndrome: Background, Pathophysiology, Etiology - Medscape

    Oct 20, 2025 · CREST (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome is a member of the heterogeneous group of sclerodermas, and its name is …

  10. CREST Syndrome: Symptoms, Causes & Treatment - Autoimmune Association

    Learn about CREST syndrome, a limited form of scleroderma causing skin hardening, Raynaud’s, calcinosis, esophageal issues, and telangiectasia.