A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, …

Once activated, the MAPK phosphorylates diverse substrates in the cytosol and nucleus to bring about changes in protein function and gene expression that execute the appropriate biological response.

This MAPK cascade (the Ras/Raf/MEK/ERK pathway) is a receptor tyrosine kinase mediated signaling pathway that regulates cell proliferation, cell cycle progression, and cell migration.

Jun 11, 2025 · Mammalian cells possess several distinct MAPK pathways, including the extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), and p38 MAPK families.

The MAPK signaling pathway is essential in regulating many cellular processes including inflammation, cell stress response, cell differentiation, cell division, cell proliferation, metabolism, motility and …

Apr 7, 2025 · MAPK's role in cell survival Mitogen-activated protein kinases (MAPKs) are a family of protein kinases that play a crucial role in relaying extracellular signals to intracellular responses, …

Dec 14, 2025 · The MAPK signal transduction cascades involve the coordination of a variety of extracellular signals that are initiated to control diverse cellular processes such as proliferation, …

Mitogen-activated protein kinase (MAPK) cascades consist of at least three protein kinase modules that are sequentially activated and are essential components of several critical signaling pathways.

Feb 7, 2025 · Cold stress (CS) significantly impacts rice (Oryza sativa L.) growth during seedling and heading stages.

The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration.